A very interesting and exciting guest talk by Mr. Tolis Lerios and his wife Christine was delivered at our main campus in Thessaloniki. CITY College students had the opportunity to hear first hand, about the experiences, the successes and the mishaps of Mr. and Mrs. Lerios, throughout their twenty year career as "serial entrepreneurs," with involvement in numerous IT companies, startups and projects in the U.S. and abroad. A long period of vivid Q and A followed the talk. The event, which was co-organized with SEERC and EPY (Greek Computers Society), was part of the Computer Science Professional Development Seminars, but it was also open to students from all departments and EPY members. The event was coorganised with EPY.